ZM 39923 hydrochloride( ZM 39923 | ZM-39923 | ZM39923 HCl )

Catalog No. M17549 CAS No. 58753-54-1

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Datasheet

HNMR

HPLC

MSDS

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Product Name

ZM 39923 hydrochloride
Note

Research use only, not for human use.
Brief Description

ZM 39923 hydrochloride is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
Description

ZM39923 HCl is a potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3).
In Vitro

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In Vivo

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Synonyms

ZM 39923 | ZM-39923 | ZM39923 HCl
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

EGFR| JAK1| JAK3| TGM2
Research Area

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Indication

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CAS Number

58753-54-1
Formula Weight

367.91
Molecular Formula

C23H25NO·HCl
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.CC(C)N(CCC(=O)c1cc2ccccc2cc1)Cc1ccccc1
Chemical Name

3-[Benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one hydrochloride

1. Brown GR, et al. Bioorg Med Chem Lett. 2000, 10(6), 575-579.

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