ZM 39923 hydrochloride

CAS No. 58753-54-1

ZM 39923 hydrochloride( ZM 39923 | ZM-39923 | ZM39923 HCl )

Catalog No. M17549 CAS No. 58753-54-1

ZM 39923 hydrochloride is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 56 Get Quote
10MG 98 Get Quote
25MG 181 Get Quote
50MG 300 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ZM 39923 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    ZM 39923 hydrochloride is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
  • Description
    ZM39923 HCl is a potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ZM 39923 | ZM-39923 | ZM39923 HCl
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    EGFR| JAK1| JAK3| TGM2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    58753-54-1
  • Formula Weight
    367.91
  • Molecular Formula
    C23H25NO·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.CC(C)N(CCC(=O)c1cc2ccccc2cc1)Cc1ccccc1
  • Chemical Name
    3-[Benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brown GR, et al. Bioorg Med Chem Lett. 2000, 10(6), 575-579.
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