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Home - Products - Cell Cycle/DNA Damage - DNA/RNA Synthesis - ZM 39923 hydrochloride

ZM 39923 hydrochloride

CAS No. 58753-54-1

ZM 39923 hydrochloride( ZM 39923 | ZM-39923 | ZM39923 HCl )

Catalog No. M17549 CAS No. 58753-54-1

ZM 39923 hydrochloride is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ZM 39923 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    ZM 39923 hydrochloride is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
  • Description
    ZM39923 HCl is a potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ZM 39923 | ZM-39923 | ZM39923 HCl
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    EGFR| JAK1| JAK3| TGM2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    58753-54-1
  • Formula Weight
    367.91
  • Molecular Formula
    C23H25NO·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.CC(C)N(CCC(=O)c1cc2ccccc2cc1)Cc1ccccc1
  • Chemical Name
    3-[Benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brown GR, et al. Bioorg Med Chem Lett. 2000, 10(6), 575-579.
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